|VIRCHOW, Rudolf. Die
Cellularpathologie in ihrer Begrundung auf physiologische und
pathologische Gewebelehre.Berlin: August Hirschwald, 1858. Octavo, modern
three-quarter calf over original boards. $5500.
First edition of one of the most
influential works in the history of medicine.
made cellular pathology into a system of overwhelming importance. His
main statement of the theory was given in a series of 20 lectures in
1858. The lectures, published in 1858 as his book Die
Cellularpathologie in ihrer Begründung auf physiologische und
pathologische Gewebenlehre (Cellular Pathology as Based upon
Physiological and Pathological Histology), at once transformed
scientific thought in the whole field of biology" (Britannica).
Virchow's theory that the changes in cells account for diseases in
organs revolutionized the field of medicine, leading to a profound
growth in the understanding of the mechanisms responsible for diseases. Provenance:
with stamp on title of Abraham Jacobi (1830- 1919), German-born American
physician who established the first clinic for children's diseases in
the United States (1860), authored many works on children's diseases,
and is considered the founder of American pediatrics. Printing and the
Mind of Man 307c. Garrison-Morton 2299. Grolier/Horblit 99. Heirs of
Hippocrates 1892. Bookplate, additional institutional stamp on title;
light wear to original boards.